Introduction: The global burden of thyroid disorders, especially hypothyroidism, is high and increasing.Prevalence studies of such disorders are limited in Nepal.The aim of this study was to find out the prevalence of hypothyroidism among patients visiting the Department of Biochemistry in the central laboratory of a tertiary care centre.Methods: A

Psychoacoustical models have been used extensively within audio coding applications over the past Metal Pipes decades.Recently, parametric coding techniques have been applied to general audio and this has created the need for a psychoacoustical model that is specifically suited for sinusoidal modelling of audio signals.In this paper, we present a n

The Enhancer of Zeste 2 (EZH2) protein has been reported to stimulate cell growth in some cancers and is therefore considered to represent an interesting new target for therapeutic intervention.Here, we investigated a possible role of EZH2 for the growth control of colon cancer cells.RNA interference (RNAi)-mediated intracellular EZH2 depletion led

The prevalence of cigarette smoking among people experiencing homelessness is 70%.The internet is a common mode of exposure to tobacco-related messaging, yet little is known about these exposures among people experiencing homelessness.Using time-location sampling, we recruited a sample of adults experiencing homelessness who were current cigarette

The Phillips Guide Rail curve shows the trade-off relationship between the inflation and unemployment rates.A rise in inflation due to the high economic growth, more jobs are available and therefore unemployment will fall.However, the existence of the Phillips curve in high-income countries has not been much discussed.Countries with high income sho